9/11/2023 0 Comments Tart cherry juice for sleep dosage![]() 1 In the few human experiments conducted with tart cherries, a cherry juice blend (CherryPharm, Inc., Geneva, NY, USA) was found to decrease oxidative stress in healthy older adults, 5 enhance muscle recovery following a single bout of strength training in a randomized clinical trial, 6 and decrease inflammation and oxidative stress following marathon running. 4 Tart cherries in particular also have high levels of anti-inflammatory substances 3 at a level comparable to a number of nonsteroidal anti-inflammatory products. 3 Levels of anthocyanins in tart cherries have been found to exceed those found in sweet cherries and other fruits. 2 One laboratory study has demonstrated a positive linear relationship between the level of anthocyanins in cherries and the degree of protection from oxidative stress in neuronal cells. Other anthocyanins like cyanidin-3-sophoroside, cyanidin-3-glucoside, and peonidin-3-glucoside make up less than 10% of the anthocyanin profile. 1 Anthocyanins are the main component of the phenolic compounds found in tart cherries and mainly consist of cyanidin-3-glucosylrutinoside and cyanidin-3-rutinoside. One such claim has been for a sleep-enhancing effect of tart cherries, the target of this pilot study.Īvailable data do support the presence of several phytonutrients in Montmorency tart cherries including the phenolic acids-chlorogenic acid, caffeic acid, and ellagic acid-and the flavonoids-isorhamnetin, kaempferol, quercetin, catechin, epicatechin, procyanidins, and anthocyanins. T art cherries are purported to have a number of beneficial health effects, although few data exist to support these claims. These effects, however, were considerably less than those for evidence-based treatments of insomnia: hypnotic agents and cognitive-behavioral therapies for insomnia. The results of this pilot study suggest that CherryPharm, a tart cherry juice blend, has modest beneficial effects on sleep in older adults with insomnia with effect sizes equal to or exceeding those observed in studies of valerian and in some, but not all, studies of melatonin, the two most studied natural products for insomnia. ![]() Effect sizes were moderate and in some cases negligible. When compared to placebo, the study beverage produced significant reductions in insomnia severity (minutes awake after sleep onset) no such improvements were observed for sleep latency, total sleep time, or sleep efficiency compared to placebo. The tart cherry juice beverage was associated with statistically significant pre- to post-treatment improvements on all sleep variables. Sleep continuity (sleep onset, wake after sleep onset, total sleep time, and sleep efficiency) was assessed by 2-week mean values from daily sleep diaries and disease severity by the Insomnia Severity Index in a cohort of 15 older adults with chronic insomnia who were otherwise healthy. ![]() The pilot study used a randomized, double-blind, crossover design where each participant received both treatment and placebo for 2 weeks with an intervening 2-week washout period. This study ascertained whether a proprietary tart cherry juice blend (CherryPharm, Inc., Geneva, NY, USA) associated with anecdotal reports of sleep enhancement improves subjective reports of insomnia compared to a placebo beverage.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |